Dosage forms can be classified into two major categories: 'Route
of administration' & ‘Physical form’.
Route of administration: A path through which a drug is taken into the body is known
as the Route of Administration. It is determined by the property of drug, therapeutic
objective, and biopharmaceutical factors.
1. Oral dosage form: When the drug is administered through the mouth
and it reaches the stomach and then gets absorbed, metabolized, and distributed to the
tissue before it exerts its therapeutic effect. Examples: tablets,
capsules, lozenges, pastilles, dental cones, granules, oral powder, and liquid preparations.
2. Topical dosage form: The application of drug directly to the surface of the skin,
mainly used for the therapeutic effects is known as the Topical dosage form. Examples:
ointments, creams, gels, poultice, pastes,
dusting powder, transdermal patch, plasters, liniments, lotions, collodion, and aerosol
sprays.
3. Rectal dosage forms: Rectal administration involves the use of the rectum as a route
of administration for medicine and other fluids, which are absorbed via the rectum's blood
vessels and flow into the body's
circulatory system, which distributes the drug to the organs and biological systems.
Examples: suppository and enema.
4. Parental dosage forms: When a drug is injected via a hollow needle into the body at
various sites and to multiple depths is known as the Parental dosage form. Examples:
Injections
5. Respiratory or Inhaled dosage form: When the medication particles are inhaled that
is breathed in through the nose or mouth is called Respiratory or Inhaled dosage form. It
includes inhaling gases, vapors, aerosols,
powders, sprays, solutions, and suspensions. Examples:
6. Viginal dosage forms: The insertion of drugs into the vaginal canal to generate
local or, less commonly, systemic pharmacological effects is referred to as vaginal dosage
forms. Examples: pessary, viginal ring,
douche, and intrauterine device.
7. Ophthalmic dosage forms: Specialized dosage forms designed to be instilled onto the
external surface of the eye or administered inside the eye are known as Ophthalmic dosage
forms. Examples: eye drops, ophthalmic
ointment, and gels, ocular inserts, intravitreal injections, and implants.
8. Nasal dosage forms: Nasal dosage form refers to the route of administration in which
medications are insufflated through the nose. It can be either topical or systemic
administration because the medications
delivered locally might have either solely local or systemic effects. Examples: nasal spray,
nose drops, aerosol spray, metered-dose nebulizer, and saturated cotton pledget.
9. Otic Dosage forms: When substances are intended for administration either on the
outer ear or into the auditory canal is known as Otic dosage forms. This is commonly used to
treat or prevent ear infections,
especially infections of the outer side of the ear canal. Examples: ear drops.
1. Solid dosage form: In the pharmaceutical industry, solid dosage
formulations are essential dosage forms. Tablets, capsules, granules, sachets, powders, dry
powder inhalers, and chewables are some examples. A unit dose
of one or more medications is included in a solid dosage form. Examples: Tablets, capsules,
granules, sachets, and powders
2. Semi-solid dosage form: Ointments, creams, and gels are Semi-solid dosage forms
intended for topical application. They may be applied to the skin, placed onto the surface
of the eye, or used nasally, vaginally,
or rectally. The majority of these preparations are used for the effects of the therapeutic
agents they contain. Those which are non-medicated are used for their physical effects as
protectants or lubricants. Topical
preparations are used for the localized effects produced at the site of their application,
although some unintended systemic drug absorption may occur, it is usually in
sub-therapeutic quantities. Examples: Ointments,
creams, pastes, gels, and suppositories.
3. Liquid dosage forms: Liquid dosage forms are made by dissolving active ingredients
in an aqueous or non-aqueous solvent, such as solutions, suspensions, and emulsions.
Substances used in liquid dosage forms
include vehicle, stabilizers and viscosity builders, preservatives, sweeteners, color, and
taste. Furthermore, solubilizers are necessary for clear liquids, suspending agents for
suspensions, and emulsifying agents
for emulsions. Examples: Collodions, nasal and eye drops, Elixirs, suspensions, and gargles.
4. Gaseous dosage forms: Gaseous dosage forms are packed in a container which gets
released upon applying pressure. The gas inside contains therapeutically active medicinal
elements. The containers have valve systems
with continuous or limited delivery. They are used for topical application on skin and as a
local application into the nose and mouth. Examples: sprays, inhalers, aerosols, vaporizers
and nebulizers, or atomizers.
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